Our research centers upon the use of environmentally-derived genome sequence information to explore the genetic potential, ecology, and evolution of marine microbial populations. The nature of this work relies equally upon field-based collections, bioinformatics (genome assembly, annotation, and comparative analyses) and the tools of molecular ecology and genetics. Together, these approaches enable us to utilize environmental genome sequence data to understand natural microbial phenomena including environmental adaptation, evolutionary processes, lateral gene transfer events, biogeographical patterning, biogeochemical cycling, microbial interactions, and in situ metabolic activity.